Sulfur Amino Acids

Investigators from Carleton University Publish New Data on Sulfur Amino Acids

Published in Obesity and Diabetes Week, March 12th, 2012

2012 MAR 12 -- According to the authors of a study from Ottawa, Canada, "S-(2-succino)cysteine (2SC) is a chemical modification of proteins produced by reaction of fumarate with thiol groups in protein, a process known as succination. We propose to use the name S-(2-succino)cysteine (instead of S-(2-succinyl) cysteine) from this point on."

"This is to distinguish protein succination (in which fumarate forms a thioether linkage with cysteine residues) from succinylation (in which an ester, thioester or amide bond would be formed). Succination of proteins is increased in muscle of type 1 diabetic rats and in adipose tissue in type 2 diabetic mice. The...

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Source: Obesity and Diabetes Week (2012-03-12)

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