Diabetes

Data on Diabetes Described by P.V.A. Babu et al

Published in Obesity and Diabetes Week, May 7th, 2012

2012 MAY 7 -- According to the authors of recent research from Blacksburg, Virginia, "Hyperglycemia-induced vascular inflammation resulting in the enhanced monocyte-endothelial cell (EC) interaction is the key event in the pathogenesis of atherosclerosis in diabetes. Here, we investigated the effect of isoflavone genistein on hyperglycemia-stimulated vascular inflammation."

"Human aortic EC (HAEC) were pretreated with genistein before the addition of high glucose (HG; 25 mmol/L) for 48 h. Genistein at a physiological concentration 10.1 mu mol/L) significantly inhibited HG-induced adhesion of monocytes to HAEC and suppressed endothelial production of...

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Source: Obesity and Diabetes Week (2012-05-07)

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