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Oncology Business Week

Susan Hasty, Publisher

Table of Contents . . . May 30th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Oncology Business Week | Other Publications

Alliance for Cancer Gene Therapy - $4 million in research grants awarded

Altarex Corp. - MAb prolongs disease-free survival in optimal chemosensitive patients

Aptamera, Inc. - Mark C. Rogers becomes chairman of oncology drug-development company

Ardais Corporation - Biorepository to be launched at Duke for clinical research in cancer

AstraZeneca - Genetic mutations of EGFR-TK confer responsiveness to Iressa

Automated Cell, Inc. - Antibody therapeutics firm receives $100,000 investment

CancerVax Corporation - Preclinical data support anti-angiogenic effects of monoclonal antibody

Digene Corporation - Milestone reached in use of DNAwithPap test

Genta, Inc. - Genasense maker reports first quarter revenues of $1.7 million

Imagine Pharmaceuticals, Inc. - San Diego, California-based pharma secures series A financing

OSI Pharmaceuticals, Inc. - Tarceva improves overall survival in non-small cell lung cancer study patients

Roche - R1549 fails to meet primary endpoint in phase III ovarian cancer study

Varian Medical Systems, Inc. - FDA issues 510k clearance for single-channel device for HDR brachytherapy

AGT Biosciences Limited - Cross border merger creates integrated pharmaceutical firm

Aichi Cancer Center -  MASL1 oncogene involved in hematological and solid tumors

Akita University - Mutant gap junction proteins alter liver cell activity

Alexis Vautrin Center, Nancy - Wild-type p53 gene transfer sensitizes cancer to photodynamic therapy

American Pharmaceutical Partners - FDA approves Cladribine injection for hairy cell leukemia

Applied Biosystems - Genes associated with survival in diffuse large B cell lymphoma identified

BioCurex, Inc. - Accuracy of serum-Recaf results on lung cancer reaffirmed

BioSphere Medical, Inc. - Device company reports 4% increase in revenue

Birmingham Women's Hospital, U.K. - Diagnostic tests for uterine condition are more accurate than estimates suggest

Boston University - c-Rel transcription factor can transform cells to malignancy in culture

Breast Cancer - Campaign supports legislation to ensure quality mammography screening

Breast Cancer - Surgical excision still necessary when core biopsy shows minimal abnormal cells

Broomfield Hospital, Essex - Researchers prepare guidelines for managing familial breast cancer

Cancer Institute Hospital, Tokyo - Human papillomavirus 18 and altered genes combine to form glassy cell carcinoma

Cancer Prevention - Xerox gives employees paid leave for up to a year for charity work

Cancer Research U.K. - Scientists unveil new clues to the secret of eternal life

Cancer Research UK - Idoxifene only modestly efficacious in breast cancer patients

Cancer Research UK - South Asian women in NE England have higher mastectomy rates than non-Asians

Cancer Therapy - Make-A-Wish kid debuts cancer-fighting video game

Cancer Trends - Wyoming cancer rates rise slightly

Caritas St. Elizabeth's, Boston - CAD a viable option for second reading of mammograms, and as MRI adjunct

Cedars-Sinai Medical Center - Mechanism enables stem cells to track migrating brain tumor cells

Central Hospital, University of Quebec - Vaginal radical trachelectomy is an alternative to radical hysterectomy

Cervical Cancer - Revised screening guidelines require re-education of women, physicians

Children's Hospital of Los Angeles - Ceramide synthesis can be targeted for the treatment of cancer

Children's Hospital of Philadelphia - The Wisconsin Card Sorting Test is sensitive to the effects of low-grade tumors

Chinese Academy of Medical Science, Beijing - Smad5 negative regulator of embryonic hematopoiesis

Cleveland Clinic Foundation - Clinical scrutiny eases outcomes for those with rectal cancer

Columbia University - New patent protects Introgen's INGN 241 cancer therapeutic

Columbus Children's Hospital - Technique efficiently delivers gene therapy to soft-tissue tumors

Dartmouth College - Study establishes electro-magnetic characteristics of healthy breast tissue

Duke University - Irinotecan plus BCNU shows low toxicity in patients with progressive glioma

E-Z-EM, Inc. - Contrast agent maker comments on virtual colonoscopy study

Echelon Biosciences, Inc. - Alliance formed to advance cell signaling cancer therapeutics

EDAP TMS S.A. - Urological device maker reports success with Ablatherm ultrasound device

Environmental Health - North Dakota human services workers get new office after cancer scare

Environmental Health - Researcher finishes collecting samples for leukemia investigation

Erasmus Medical Center, Rotterdam - (-7,-5)pro-PSA and human kallikrein-2 are ineffective in grading prostate cancer

FASgen, Inc. - Advances in pharmacotherapy of obesity reviewed

Federico II University - Ultrasound-guided biliary endoscopy safe and effective

Firat University, Elazig - Vitamin A, E, C, and selenium may help prevent and treat bladder cancer

Fitness & Wellness - Study shows obese kids more likely to be bullying victims and aggressors

Food Safety - Johns Hopkins studies arsenic in chicken feed

Foothills Provincial General Hospital - Thinprep-prepared cytology comparable with conventional methods

Funding - Nevada inmates raise $6,500 for breast cancer

Fundraising - Two-day walk for breast cancer research and care ends in Washington, DC

Genmab, A/S - Company announces positive HuMax-CD4 phase II lymphoma data

GenVec Inc., Gaithersburg - Adenovirus vector libraries provide clues about gene and protein function

Georgetown University - Tumor-targeting immunolipoplexes improve with pH-sensitive peptide attachment

German Cancer Research Center - Neutralization of CD95 ligand enhances post-trauma spinal cord recovery

German Cancer Research Center, Heildelburg - NO66 has role in ribosome biogenesis and replication of heterochromatic regions

German Center for Research in Aging, Heidelberg - Study evaluates quality of life of breast cancer patients 1 year after diagnosis

Harvard Institute of Medicine - ESE-1 cultivates angiopoietin-1 expression in inflammatory environments

Harvard University - Impaired IgA class switching found in APRIL-deficient mice

Health Enhancement Products, Inc. - Company applies for patent covering ProAlgaZyme product

Healthcare Quality - Study says U.S. health care not always best in world

Hellenic Air Force Hospital - Optimal management of ductal carcinoma in situ of the breast described

Herlev University Hospital - MAUS is insufficient for routinely diagnosing transitional cell bladder tumors

Hokkaido University - Overexpressed pigment epithelium-derived factor arrests melanoma cell growth

House Ear Clinic and House Ear Institute - Microsurgical removal of skull-base tumors effective in preserving function

I-Flow Corp. - Drug-delivery company reports Q1 revenue increased 40% to record $14.2 million

ILEX Oncology Inc. - Oncology company reports strong Q1 driven by continued growth of CAMPATH

Institute of Cancer Research - Therapies that exploit heat shock protein 90 target cancer growth

Instituto Nacional de Cancerologia - Study of surgical site infections in breast surgery reported

International Agency for Research on Cancer, Lyon - Frameshift mutations at the Dok1 gene mark chronic lymphocytic leukemia

Introgen - Data published describing novel mechanism of mda-7 anticancer activity

Introgen Therapeutics - New data describe tumor-killing activity of Advexin

Jackson Memorial Hospital - Campath immunosuppression causes earlier development of LP infiltrates

Johns Hopkins University - Arsenic in chicken feed studied

Johns Hopkins University - Combo PET/CT recommended to determine stage of non-small-cell lung cancer

Johns Hopkins University - Rare esophageal cancer in African Americans may differ from whites

Jose de San Martin Hospital Clinic - Inhibition of tumor galectin-1 gene expression promotes T cell-induced rejection

Keck School of Medicine - Hepatitis C virus uses hit-and-run mechanisms to boost cancer formation

Keck School of Medicine - The journey to hereditary nonpolyposis colorectal cancer begins at birth

Korea Advanced Institute of Science & Technology - Self-assembled nanoparticles shepherd RGD peptide to tumor vessels

Kurume University - HER2/neu peptides recognized by cellular and humoral immune systems

Kyoto Prefectural University of Medicine - Dual-color tissue-FISH facilitates t(14;18) detection in follicular lymphoma

Kyoto University - RUNX3 gene expression is often lost from gastric cancer cells

Kyushu University - Cyclooxygenase 2 stimulates interleukin-1beta-induced angiogenesis

Kyushu University - Heart attack models benefit from therapy suppressing tumor necrosis factor

La Jolla Institute of Molecular Medicine - Truncated fibroblast growth factor-2 halts tumor proliferation

Legal Issues - Florida couple sentenced for letting teen's cancer go untreated

Legal Issues - Oregon woman files suit against large pharmaceutical companies

Linkoping University - BRAF and KRAS gene mutations drive colorectal adenocarcinoma formation

London School Hygiene & Tropical Medicine - Childhood growth is related to breast cancer risk

Ludwig Inst. for Cancer Research - Expression profiles of 6000+ genes in normal breast cells determined

M.D Anderson Cancer Center - Full-field digital mammography is faster for needle localization

M.D. Anderson Cancer Center - A combined regimen is active against refractory acute myelogenous leukemia

M.D. Anderson Cancer Center - Bone marrow-derived stem cells used for potential treatment of gliomas

M.D. Anderson Cancer Center - Increased plasma levels of two IGFs associated with disease risk

M.D. Anderson Cancer Center - New findings contradict conventional views about hTERT and breast cancer

M.D. Anderson Cancer Center - Researchers develop a simple method to estimate global DNA methylation changes

M.D. Anderson Cancer Center - Utility of FACS immunophenotyping evaluated

Massachusetts General Hospital - Coronal reformatting of axial images from 16-MDCT helps stage ovarian cancer

Massachusetts General Hospital - Thoracic PET appropriate for diagnosing some lung cancer patients

Mayo Clinic - Study evaluates Internet resources and printed materials for smoking cessation

Medical College of Virginia Hospitals - CT pulmonary angiography in women delivers high radiation dose to breast

MediGene, AG - Phase II clinical trial of Polyphenon E Ointment begins

Memorial Sloan-Kettering Cancer Center - Physicians should discuss palliative care with terminal rectal cancer patients

Memorial Sloan-Kettering Cancer Cntr. - Cancerous lesions show "surprising characteristics" on MRI

Memorial Sloan-Kettering Cancer Cntr. - Researchers confirm genetic link between hereditary breast, prostate cancer

Mersin University - Matrix metalloproteinase marks the course of Hodgkin and non-Hodgkin lymphoma

Mersin University, Oxford - CD7 and CD56 antigens associated with low remission rate in acute leukemia

Misonix, Inc. - Focus signs agreement with USHIFU to fund prostate cancer clinical trials

Mt. Sinai School of Medicine, New York - ETO interaction domains within N-CoR first step in AML molecular therapy design

Mt. Vernon Hospital, Northwood - Tissue microarray validated for immunohistochemical melanoma analysis

Nanjing Medical University - XRCC3 DNA repair gene variants can't account for gastric cancer in China

National Academy of Sciences of Belarus - Outdoor air pollution causes many cancer-related deaths in Russia

National Cheng Kung Univ. Hospital, Tainan - Benign mucocele-like lesions can be differentiated from mucinous carcinoma

National Univ. of Singapore Hospital - Medullary breast cancers are not an indication for BRCA1 mutation screening

National University of Cordoba -  Aloe saponaria mannan has potent anticancer effects

National Yang Ming University - D-loop mutations and decreased mtDNA copy number preface liver cancer

NeoRx Corp. - Cancer therapeutics company names Jerry McMahon CEO; Jack Bowman to retire

Netherlands Cancer Institute - IGF expression higher in tissue of women at high breast cancer risk

Netherlands Cancer Institute, Amsterdam - Drug transporters confer resistance against nucleoside-analog-based antivirals

Neurobiological Technologies, Inc. - XERECEPT pivotal phase III trial begins

New York University - Elderly black male cancer patients hospitalized longer than white

New York University - Ras proto-oncogenes can have different effects in tumorigenesis

Niigata University - Alphaviruses could bridge the vector gap in cancer gene therapies

Northwestern Memorial Hospital, Chicago - Digital mammography takes longer to interpret than screen-film version

Northwestern University - Drugs leave brain tumors rapidly after convection-enhanced delivery

Northwestern University - Study finds MRI 'highly useful' in evaluating patients with uterine fibroids

Northwestern University - Tissue microarray valuable for validation of HER2 FISH testing

Obstetrics - Preterm delivery associated with treatment for precancerous cervical changes

Ohio State University - Chromosome losses may mean poor survival in childhood leukemia

Ohio State University - Taxanes may enhance patients' immunity

Okayama University - Response in pRL1a multiple antigen peptide-immunized mice reported

Oregon Health and Science University - IGF-binding protein induces apoptosis in breast cancer cells

Osaka University - Angiopoietin-2 encourages the metastatic evolution of colorectal cancer

Patient Education - Most women unaware of health concerns that affect them differently than men

Pediatric Obesity - Obese kids more likely to be bullied

Personnel - HMO founder Maurice Lazarus dead at 88

Pharmacology Laboratory, Creteil - Curcumin uses iron reduction to stimulate mitochondrial membrane permeability

Premier, Inc. - Sole-source group buy agreement announced for ImageChecker CAD Systems

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