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Matrix metalloproteinase marks the course of Hodgkin and non-Hodgkin lymphoma

Published in Oncology Business Week, May 30th, 2004

Matrix metalloproteinase marks the course of Hodgkin and non-Hodgkin lymphoma.

"Matrix metalloproteinases (MMPs) are responsible for the degradation of extracellular matrix and have an important role in turnout metastases. We investigated the role of MMP-2 and MMP-9 in Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL). The serum samples of patients with HD (n=12), NHL (n=30) and healthy control (n=22) were analyzed for MMP-2 and MMP-9," scientists writing in the International Journal of Clinical Practice report.

"An immunoassay method was used for the determination of MMP-2 and MMP-9 levels. No statistical significance was found between...

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