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Oncology Business Week

Susan Hasty, Publisher

Table of Contents . . . June 27th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Oncology Business Week | Other Publications

Adherex Technologies, Inc. - Biopharmaceutical company reports loss of $0.02 per share

Attenuon, L.L.C. - Phase I trial of ATN-224 initiated in patients with solid tumors

Cepheid - NCI $1.9M grant awarded for GeneXpert platform research

Favrille, Inc. - FDA issues special protocol assessment for phase III trial of FavId

GlobeImmune, Inc. - New phase I cancer trial planned

HealthEast - First Minnesota hospital to use robot-assisted technology in prostate cancer surgery

MedPanel, Inc. - Life sciences research and information company launches new publication

Peregrine Pharmaceuticals - Ligand-based VTA technology presented at international conference

Pfizer Inc. - Chemotherapy including epirubicin may improve survival for some patients

Pharmion Corporation - FDA approves Vidaza (azacitidine for injectable suspension) for MDS

Rockefeller University - Cell growth and death controlled by single pathway in cancer model

Varian Medical Systems, Inc. - Cancer therapy systems manufacturer adds eighth member to board of directors

Stadtisches Klinikum Braunschweig - Researchers advocate adjuvant therapy in high-risk prostate cancer

AMDL, Inc. - U.S. patent granted for its Immunogene therapy for cancer

Adelaide University - Apo2L/TRAIL and doxorubicin increases sensitivity to bone sarcomas

Advanced Magnetics, Inc. - Nanoparticles illuminate brain tumors for days under MRI

American University of Beirut - Effective rituximab treatment of B-cell PLL reported

American University of Beirut - Quinoxaline 1,4-dioxides potentiate the effects of ionizing radiation

Amino Up Chemical Co. - Men on "watchful waiting" eligible for soy-mushroom extract trial

Aphton Corporation - Results of phase II study of G17DT vaccine reported

Arcturus Bioscience, Inc. - Gene expression ratio identifies recurrence risk in patients receiving tamoxifen

Artificial Heart - Man-made heart provides woman new lease on life

Breast Cancer - Advanced diagnosis more likely for deprived women in the U.K.

British Columbia Cancer Agency - Minimal region of deletion implicates four genes in follicular lymphoma

CLCC Francois Baclesse, Caen - Women with thyroid carcinoma at higher risk for second primary cancer

CNRS, Chatenay Malabry - Gel-entrapped tamoxifen offers sustained drug release at tumor sites

CNRS-UMR 5160, Montpellier - ABCG2 may be involved in the evolution of colon cancer drug resistance

Cancer Research U.K. Cntr. for Cancer Therapeutics - High-throughput screening detects heat-shock protein 90 ATPase inhibitors

Cancer Treatment - Utah doctors determine 'good, bad' chemo

Carlo Besta National Inst. of Neurology - CXCL12 supports the angiogenesis and cellular cross-talk of glioma

Cell Therapeutics, Inc. - Enrollment completed in pivotal trial of Xyotax

Chang Gung Memorial Hospital - Breast metastases from extramammary malignancies are rare

Children's Cancer Inst. of Australia for Med. Res. - Short-term morphine exposure doesn't subdue multidrug resistance

Children's Medical Research Inst., Sydney - p16(INK4a) and p53 tumor suppressor genes altered in hTERT-immortalized cells

Cleveland Clinic - Study reviews cancer-associated anorexia

Cleveland Clinic Foundation - Genetic differences in ethnic groups affect the chronicity of hepatitis C

Cornell University - HHV-8 vFLIP essential for survival of infected lymphoma cells

Dartmouth College - MART1/MelanA stains have high false-positive rate

Decision Resources, Inc. - Rituximab called most promising emerging drug for chronic lymphocytic leukemia

Dokkyo University - Etodolac staunches colitis-induced tumors in rodent models

Duke University - Acquired periostin expression promotes breast cancer angiogenesis

Duke University - Benefits of screening for lung cancer with CT are not proven

Duke University - Surprising new evidence highlights adverse effects of vitamin C on arthritis

Duksung Women's University - TIMP-2 gene transfer halts H-ras-induced breast endothelial cell invasion

Enzon Pharmaceuticals, Inc. - FDA accepts Onco TCS new drug application

Erasmus Medical Center - High CD33-antigen levels limit gemtuzumab efficacy

Fred Hutchinson Cancer Center - Yo-yo dieting may have a long-term negative effect on immune function

Fred Hutchinson Cancer Research Center - Pluripotent stem cell line expressing the AML1-ETO fusion protein established

Fred Hutchinson Cancer Research Center - Study finds no association between marijuana use and incidence of oral cancer

Geller Rudman, PLLC - Class-action suit filed over brain cancer drug

GlaxoSmithKline - Drug shrinks tumors or slows growth in up to half of women

Gunma University - Oral PSK with UFT reduced recurrence in colorectal cancer

Hammersmith Hospital - Androgens work through prohibitin to steer prostate cancer growth

Harvard University - CEACAM6 crosslinking leads to increased extracellular matrix component adhesion

Harvard University - Exposure to light at night may increase cancer risk

Hillman Cancer Center, Pittsburgh - Regenerative response in ischemic brain is restricted by p21(Cip1/waf1)

Hiroshima University - Immunosuppressants may hasten oncogenesis in patients with p53 mutations

Hospital Bretonneau, Tours - Docetaxel is active against squamous cell carcinoma of the head and neck

Hospital Henri Mondor, Creteil -  Helicobacter pylori is associated with gastric cancer

IMI International Medical Innovations Inc. - Lung screening test may prove useful as first line of lung cancer testing

Institute Gustave Roussy, Villejuif - Electrochemotherapy may be a new treatment for solid tumors

Institute Gustave Roussy, Villejuif - Metastatic potential may be a genetic feature of the primary tumor

Kagawa University - Cyclin-dependent kinase 4 may foster liver cancer formation

Karolinska Hospital - Maternal smoking may play etiologic role in testicular cancer

Karolinska Institute - PET may become invaluable for diagnosing and treating brain tumors

Keio University - Thalidomide treats multiple myeloma by targeting bone marrow angiogenesis

Legal Issues - Taxol settlement brings Coloradans $430

Leiden University - Bispecific antibody works against micrometastatic renal cell carcinoma

Ludwig Institute for Cancer Research - Transforming growth factor-beta 1 regulates several endothelial cell proteins

Mayo Clinic - Liver transplantation is feasible for neuroendocrine tumors

Memorial Sloan-Kettering Cancer Center - Concordance between HER-2 testing methods determined

Nara Institute of Science & Technology - Novel PCR-array system useful for gene expression profiling

National Cancer Center - Chemotherapy after cytoreductive surgery for ovarian cancer beneficial

National Cancer Center, Japan - Study cautions about compounds produced during cooking of meat, fish

National Taiwan University - Cell death induced by vaccine adjuvants containing surfactants

Netherlands Cancer Institute - In vivo bioluminescence imaging reveals tumor elements in animal models

New York University - New animal models show the carcinogenic synergy of UV radiation and arsenic

Novartis - Recurrent disease with a molecular alteration may respond to targeted therapy

Okayama University Hospital - Patients with locally advanced lung cancer benefit from chemoradiotherapy

Oncolytics Biotech Inc. - Patient treatment begins in Reolysin trial for metastatic solid tumors

Pacific Northwest Research Institute - Melanoma cells expressing CD83 induce antitumor immunity

inGenium Research, Inc. - Contract research organization to help develop monoclonal antibody for lymphoma

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