Johns Hopkins University

Once given "no respect," cells' tiny RNAs take driver's seat

Published in Oncology Business Week, July 3rd, 2005

Ribonucleic acid, or RNA, has long been thought to be important only to translate a gene's DNA into the proteins that are cells' workhorses. But new evidence shows that tiny bits of RNA not used to make proteins actually play central roles in normal biology and in the development of cancers.

"Scientists have known for a few years that production of these tiny RNAs, known as microRNAs, is only supposed to happen at certain times and in certain tissues, but no one had been able to identify what controlled the timing," said Joshua Mendell, MD, PhD, assistant professor in the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University. "We've identified the...

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Source: Oncology Business Week (2005-07-03)

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