Louisiana State University
Gene therapy may purge leukemia cells from hematopoietic progenitor cells
Published in Oncology Business Week, December 11th, 2005
"Although viable gene therapy based methods have been reported for the selective removal or purging of contaminating epithelial derived cancer cells from stem cell grafts, similar strategies for the purging of leukemia cells have been significantly less efficient."
"Hematopoietic cells are difficult targets for transduction with currently available vectors. Polylysine based molecular conjugate vectors (MCV) were previously found to effectively transduce both normal and malignant hematopoietic cells. A panel...
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