Institut National de la Sante et de la Recherche Medicale, Reims
Lung carcinomas in Western Europe show low prevalence of human papillomaviruses
Published in Oncology Business Week, January 29th, 2006
According to recent research from France, "High-risk HPV are largely implicated in the carcinogenesis of cervical carcinomas. Their role in bronchopulmonary carcinomas is still unclear."
"In the present study, we have explored 218 fresh frozen lung tumors for the presence of HPV with the Roche line blot assay and for the expression of mRNAs encoding E6 oncoprotein in HPV positive tumors. Only 4 samples were positive for HPV detection, 1 poorly differentiated squamous cell carcinoma and 3 large cell carcinomas. E6 mRNA was...
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