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Cold Spring Harbor Laboratory

Researchers identify two genes that are likely to play a role in liver cancer

Published in Oncology Business Week, July 23rd, 2006

By generating tumors in laboratory mice that mimic human liver cancer and by comparing the DNA of mouse and human tumors, researchers at Cold Spring Harbor Laboratory have identified two genes that are likely to play a role in the third leading cause of human cancer deaths.

The study also establishes an efficient and adaptable method for exploring the biology of liver cancer, for validating potential therapeutic targets, and for testing new treatments. The findings are reported in the journal Cell.

"There has been a long search for animal models that could be predictive of the genes involved in human cancers. These researchers have taken a...

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