CuraGen

CuraGen and TopoTarget initiate Phase II clinical trial with PXD101 for mesothelioma

Published in Oncology Business Week, July 23rd, 2006

CuraGen Corporation (CRGN) and TopoTarget A/S (TOPO) announced the initiation of patient dosing in a Phase II clinical trial evaluating the activity of PXD101, a small molecule histone deacetylase (HDAC) inhibitor, for the treatment of mesothelioma.

This trial is being sponsored by the National Cancer Institute (NCI) under a Clinical Trials Agreement with CuraGen for the clinical development of PXD101.

The Phase II clinical trial is an open-label study being led by Suresh Ramalingam, MD, assistant professor of medicine at the University of Pittsburgh School of Medicine in Pittsburgh, Pennsylvania. Patients with unresectable malignant pleural...

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Source: Oncology Business Week (2006-07-23)

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