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Allergy & Immunology

Dynavax reports interim Tolamba ragweed allergy results from DARTT trial

Published in Oncology Business Week, February 11th, 2007

Dynavax Technologies Corporation (DVAX) announced that the analysis of interim one-year data from its two-year DARTT ragweed allergy trial indicated that no meaningful ragweed-specific allergic disease was observed in the study population, making it impossible to measure the therapeutic effect of Tolamba treatment.

In all three arms of the study, including the placebo arm, minimal change from baseline was observed in the main efficacy measure of the study, the total nasal symptom score (TNSS). The company indicated that in the placebo and treated groups, the change from baseline TNSS was very low; not clinically significant; and substantially lower than what has been...

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