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Cancer Therapy

Research results from Rikshospitalet-Radiumhospitalet Medical Center update knowledge of cancer therapy

Published in Oncology Business Week, May 27th, 2007

Researchers detail in "Tobramycin once versus three times daily, given with penicillin G, to febrile neutropenic cancer patients in Norway: a prospective, randomized, multicentre trial," new data in cancer. According to a study from Oslo, Norway, "Penicillin G with an aminoglycoside is the standard initial empirical treatment in febrile neutropenia in Norway. It has been argued that giving the aminoglycoside once daily to neutropenic patients with Gram-negative bacteraemia may be hazardous when penicillin G is the beta-lactam antibiotic."

"We questioned this argument and hypothesized that tobramycin once daily was as efficacious as three times daily. We conducted a...

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