Gene Therapy
New gene therapy research reported from Jichi Medical University
Published in Oncology Business Week, May 27th, 2007
Investigators publish new data in the report "Transforming activity of purinergic receptor P2Y, G-protein coupled, 2 revealed by retroviral expression screening." According to recent research from Tochigi, Japan, "Colorectal cancer (CRC) is one of the leading causes of cancer death in humans. In order to identify novel cancer-promoting genes in CRC, we here constructed a retroviral cDNA expression library from a CRC cell line RKO, and used it for a focus formation assay with mouse 3T3 fibroblasts, leading to the identification of 42 independent cDNAs."
"One of such cDNAs turned out to encode purinergic receptor P2Y, G-protein coupled, 2 (P2RY2). The oncogenic potential...
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