Glioma
Research from P.S. Kumar and co-authors reveals new findings on glioma
Published in Oncology Business Week, October 14th, 2007
According to recent research from Pune, India, "The role of TNF-alpha in affecting the fate of tumors is controversial, while some studies have reported apoptotic or necrotic effects of TNF-alpha, others provide evidence that endogenous TNF-alpha promotes growth and development of tumors. Understanding the mechanism(s) of TNF-alpha mediated growth arrest will be important in unraveling the contribution of tissue associated macrophages in tumor resistance."
"The aim of this study was to investigate the role of Cyclin Dependent Kinase Inhibitors ( CDKI) - p21(cip/waf1) and p(27kip1) in TNF-alpha mediated responses in context with p53 and activation of NF-kappa B and Akt...
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