Squamous Cell Carcinoma

New squamous cell carcinoma study results from Inje University described

Published in Oncology Business Week, October 14th, 2007

"The loss of p27 indicates a poor prognosis in various solid tumors, and a decrease in p27 level is the result of increased degradation by Skp2. We evaluated the relationship of p27 and Skp2 protein expression to various clinicopathologic factors in 332 cases of untreated uterine cervical neoplasm using tissue microarray method," researchers in Seoul, South Korea report.

"After immunohistochemical staining, 313 and 300 tumor samples were retrieved for interpretation for p27 and Skp2, respectively. High p27 protein expression (nuclear staining in more than 30% of the tumor cells) was seen in 39.9% (125/313 cases), including 32 cervical intraepithelial neoplasia (CIN) 111...

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Source: Oncology Business Week (2007-10-14)

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