Meningioma

Recent findings in meningioma described by W.K. Pfisterer and colleagues

Published in Oncology Business Week, March 23rd, 2008

"The fluorescence in situ hybridization (FISH) technique was used in 111 WHO grades I and II meningioma patients. Clinical, radiological, pathological, and immunohistochemical data were compared to aberrations of chromosomes 1p, 14q, and 22q determined by FISH," investigators in Vienna, Austria report.

"Significant differences for MIB-1 labeling were found between grades I and II tumors (p < 0.001), and between grade I tumors that recurred and those that did not recur (p < 0.001). Chromosomal aberrations were detected with FISH analysis in nearly 50% of grade I, and in 93% of grade II meningiomas. The numbers of chromosomal aberrations correlated significantly to...

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Source: Oncology Business Week (2008-03-23)

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