Colon Cancer
New colon cancer study findings recently were published by researchers at University of Pisa, Department of Internal Medicine
Published in Oncology Business Week, October 12th, 2008
A report, 'Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation,' is newly published data in British Journal of Pharmacology. "Cyclooxygenase-2 (COX-2) is expressed in colonic neoplasms, where it supports cell proliferation via prostaglandin E(2) (PGE(2)) production. This study investigated the effects of somatostatin-14 on COX-2 expression, PGE(2) production and proliferation in colon cancer cells," researchers in Pisa, Italy report.
"EXPERIMENTAL APPROACH: Human colon adenocarcinoma cell lines Caco-2, HT-29 and HCT116 were used. The following techniques were employed: colourimetric assay for cell growth; 5-bromo-2'-deoxyuridine...
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