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Tigris Pharmaceuticals, Inc.

Tigris Pharmaceuticals Files IND Application for GGTI-2418

Published in Oncology Business Week, February 22nd, 2009

Tigris Pharmaceuticals, Inc., a privately held drug development company, announced that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) for GGTI-2418, a novel anticancer compound. GGTI-2418 is a synthetic peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase I) that appears to induce apoptosis by downregulating several pivotal oncogenic and tumor survival pathways.

"The filing of this IND ahead of the scheduled date represents a major corporate achievement for the entire Tigris team," said Edmundo Muniz, M.D., Ph.D., President and Chief Executive Officer of Tigris. "Pending acceptance by the FDA, we...

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