Colon Cancer

Researchers at Chinese University of Hong Kong target colon cancer

Published in Oncology Business Week, May 3rd, 2009

According to recent research published in the journal Anticancer Research, "ErbB receptors and their cognate ligands are implicated in cancer progression. Their expression in gastrointestinal cancer, however, has not been systemically studied."

"The expression of four ErbB receptors and a panel of ErbB ligands were determined by reverse transcription-PCR in two gastric (TMK1, MKN-45) and two colon (SW1116, HT-29) cancer cell lines. Cell proliferation was measured by MTT assay while gene knockdown was achieved by RNA interference. ErbB1, ErbB2 and ErbB3 receptors and five known or putative ErbB ligands, namely, epiregulin, epidermal growth factor (EGF),...

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Source: Oncology Business Week (2009-05-03)

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