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Carcinogenesis

Studies from Cancer Research Center, Department of Molecular yield new data on carcinogenesis

Published in Oncology Business Week, May 24th, 2009

New research, 'Super competition as a possible mechanism to pioneer precancerous fields,' is the subject of a report. "Cancer is the result of sequential genetic changes over time that transform a cell into a malignant and ultimately invasive entity. The insight that cancerous cells arise from a series of mutations in oncogenes and tumor suppressors, commonly known as multistep carcinogenesis, has been conceptually elaborated and proven in the last 20 years," investigators in Madrid, Spain report.

"Although knowledge about late steps of cancerogenesis and disease progression has greatly advanced, the initial molecular events remain largely unknown. Basic research in...

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