Breast Cancer

Reports from F.C. Martins and co-researchers add new data to research in breast cancer

Published in Oncology Business Week, July 26th, 2009

According to a study from Coimbra, Portugal, "Expression of GLUT-1. and transglutaminase 2 is increased in aggressive breast cancer, whereas claudin-1, which is expressed in normal tissues, is absent in such tumors. This experimental study was undertaken to establish the aggressiveness and prognosis of DMBA-induced mammary tumors in female Wistar rats based on the assessment of these markers."

"The rats were divided into two groups, a control group (n = 70) and a chemoprevention group (n = 70). Breast tumors were induced in both groups by administration of 7,12-dimethylbenz[a]anthracene (DMBA). The chemoprevention group also received alpha-tocopherol and a solution of...

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Source: Oncology Business Week (2009-07-26)

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