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4SC AG

4SC Announces First Patient Treated in a Phase II Hodgkin's Lymphoma Study with HDAC Inhibitor Resminostat 4SC-201

Published in Oncology Business Week, January 31st, 2010

4SC AG (Frankfurt, Prime Standard: VSC), a drug discovery and development company focused on autoimmune and cancer indications, announced the treatment of the first patient in a Phase II study evaluating resminostat (4SC-201), an oral pan-histone-deacetylase (HDAC) inhibitor in relapsed or refractory Hodgkin's Lymphoma (HL) patients.

In this open-label, single-arm, Simon-design two-stage Phase II study entitled 'SAPHIRE', resminostat will be given orally at a dose of 600mg daily for five consecutive days, followed by a nine day treatment free period ('5+9' dosing schedule). In the main phase of the trial, patients will receive treatment for six cycles (12 weeks)....

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