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Data on life sciences published by researchers at California Institute of Technology, Institute of Technology

Published in Oncology Business Week, January 31st, 2010

According to a study from the United States, "The mouse gamma-minobutyric acid (GABA) transporter mGAT1 was expressed in neuroblastoma 2a cells. 19 mGAT1 designs incorporating fluorescent proteins were functionally characterized by [H-3] GABA uptake in assays that responded to several experimental variables, including the mutations and pharmacological manipulation of the cytoskeleton. Oligomerization and subsequent trafficking of mGAT1 were studied in several subcellular regions of live cells using localized fluorescence, acceptor photobleach Foster resonance energy transfer (FRET), and pixel-by-pixel analysis of normalized FRET (NFRET) images."

"Nine constructs were...

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