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Non-Hodgkin Lymphoma

New findings from Chonnam National University describe advances in non-hodgkin lymphoma

Published in Oncology Business Week, January 31st, 2010

According to a study from South Korea, "Drug metabolizing genes are involved in the detoxification of chemical carcinogens. Polymorphisms in drug-metabolizing genes affect the risk of some forms of cancer."

"We analyzed six polymorphisms to evaluate their association with risk for non-Hodgkin lymphoma (NHL), and to examine whether smoking modifies these associations in population-based study in Korea (713 cases and 1,700 controls). The GSTP1 rs1695 AG and the combined AG/GG genotypes were associated with decreased risk of NHL (odds ratio (OR)(AG) = 0.67, 95% confidence interval (CI) = 0.55-0.82; ORAG/GG = 0.66, 95% CI = 0.54-0.80) and DLBCL (ORAG = 0.63, 95% CI =...

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