Colon Cancer

New colon cancer findings from R.N. Jorissen and co-authors described

Published in Oncology Business Week, February 14th, 2010

According to a study from the United States, "Colorectal cancer prognosis is currently predicted from pathologic staging, providing limited discrimination for Dukes stage B and C disease. Additional markers for outcome are required to help guide therapy selection for individual patients."

"A multisite single-platform microarray study was done on 553 colorectal cancers. Gene expression changes were identified between stage A and D tumors (three training sets) and assessed as a prognosis signature in stage B and C tumors (independent test and external validation sets). One hundred twenty-eight genes showed reproducible expression changes between three sets of stage A and...

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Source: Oncology Business Week (2010-02-14)

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