Journal of the National Cancer Institute

Lower detection of prostate cancer with PSA screening in US than in a European randomized trial

Published in Oncology Business Week, February 28th, 2010

Fewer prostate cancers were detected by prostate-specific antigen (PSA) screening in the U.S. than in a European randomized trial because of lower screening sensitivity, according to a new brief communication published online February 8 in the Journal of the National Cancer Institute.

To compare the PSA screening performance in a clinical trial with that in a population setting, Elisabeth M. Wever, MSc, Department of Public Health, Erasmus Medical Center, the Netherlands, and colleagues applied a microsimulation model developed for prostate cancer and screening to the European Randomized Study of Screening for Prostate Cancer (ERSPC)-Rotterdam. The model was adapted by...

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Source: Oncology Business Week (2010-02-28)

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