Advaxis, Inc.
USPTO Grants Advaxis New Listeria Based Fusion Protein Patent
Published in Oncology Business Week, March 21st, 2010
The US Patent and Trademark Office (USPTO) has issued Advaxis, Inc., (OTCBB: ADXS), the live, attenuated Listeria monocytogenes (Listeria) immunotherapy company, patent #7662396 titled "Compositions and Methods for Enhancing the Immunogenicity of Antigens" for the use of fusion proteins that have been found to be effective in numerous models for the treatment of cancer in the presence of immune tolerance.
The patent covers the use of this antigen-adjuvant family of proteins alone or when delivered via a live, attenuated Listeria vaccine. Advaxis has patents on two families of antigen-fusion proteins based upon the Listeria proteins Act-A and LLO.
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