Hepatocellular Cancer
Findings from University Hospital provide new insights into hepatocellular cancer
Published in Oncology Business Week, March 21st, 2010
According to recent research published in the International Journal of Oncology, "Xanthohumol, the major prenylated chalcone found in hops, is well known to exert anti-cancer effects, but information regarding the impact on hepatocellular carcinoma (HCC) cells and potential adverse effects on non-tumorous hepatocytes is limited. Here, we show that xanthohumol at a concentration of 25 mc M induced apoptosis in two HCC cell lines (HepG2 and Huh7)."
"Furthermore, xanthohumol repressed proliferation and migration, as well as TNF induced NF-kappa B activity and interleukin-8 expression in both cell lines at even lower concentrations. In contrast, xanthohumol...
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