Glioma Cell Biology

Research from INSERM in glioma cell biology provides new insights

Published in Oncology Business Week, April 4th, 2010

Current study results from the report, 'Neuropilin-2 acts as a modulator of Sema3A-dependent glioma cell migration,' have been published. According to a study from Strasbourg, France, "Semaphorin 3A (Sema3A) is a secreted guidance molecule initially described in the nervous system. This protein is able to control axon growth but also effects on endothelial cells migration."

"Here, we report that Sema3A acts as a chemorepellent factor for the rat C6 glioma cells and three different human glioma cell lines. Interestingly, Sema3A triggered a chemoattractive response in a fourth human glioma cell line. The nature of the receptor complex ensuring the appropriate signaling...

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Source: Oncology Business Week (2010-04-04)

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