Muscular Dystrophy

Intra-Arterially Injected Stem Cells Can Bind To Muscles, Regenerate Growth

Published in Pain and Central Nervous System Week, March 31st, 2001

by N.R. Saltmarsh, staff medical writer - Gene therapy directed to muscles via arterial injection appears able to stimulate muscle re-growth in mice. The applications of this delivery system for muscular dystrophy patients are promising.

Delivery of cell or gene therapy to Duchenne muscular dystrophy patients has been stymied by the difficulty of injection directly into wasted muscles. Researchers working in Italy proposed to overcome that obstacle using intra-arterial injection of stem cells that could target lesions.

"We showed that stem cell antigen 1 (Sca-1), CD34 double-positive cells purified from the muscle tissues of newborn mice are...

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Source: Pain and Central Nervous System Week (2001-03-31)

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