Peripheral Neuropathy

Understanding nerve degeneration may lead to new treatments

Published in Pain and Central Nervous System Week, November 18th, 2002

In disorders called peripheral neuropathies, nerve fibers typically whither and die back toward their nerve cell bodies. In a study presented at the American Neurological Association's 127th annual meeting in New York City, researchers were surprised to find that this is probably caused by damage to the far end of the nerve fiber, and not to the nerve cell body that nourishes it.

"This suggests that in patients with peripheral neuropathy, we may need to direct delivery of neuroprotective agents to nerve terminals rather than to cell bodies," said lead author Jonathan D. Glass, MD, of Emory University in Atlanta.

Peripheral neuropathies encompass a...

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Source: Pain and Central Nervous System Week (2002-11-18)

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