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Stroke

Strategy may protect brain against stroke, Parkinson and Alzheimer

Published in Pain and Central Nervous System Week, November 18th, 2002

Researchers at the National Institutes of Health have developed several drug candidates that show promise in animal studies in protecting the brain against sudden damage from stroke, with the potential for fighting chronic neurodegenerative conditions like Parkinson and Alzheimer disease.

The drugs, called p53 inhibitors, attack a key protein involved in nerve cell death and represent a new strategy for preserving brain function following sudden injury or chronic disease, according to the researchers.

Their findings appeared in the November 7, 2002, print issue of the Journal of Medicinal Chemistry.

"This is a completely...

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