Estrogen Receptors
Spinal cord's neurons with estrogen receptor-alpha upregulated during pregnancy
Published in Pain and Central Nervous System Week, February 10th, 2003
"Estrogen receptor (ER) immunoreactivity and mRNAs are present in spinal cord neurons in locations that are associated with sensory and autonomic innervation of female reproductive organs. The present study was undertaken to examine the expression of estrogen receptor alpha-in the spinal cord during different stages of pregnancy and to determine whether ERalpha-expressing neurons are related to uterine afferent nerves bringing information to the spinal cord at parturition," researchers in the United States report.
"Immunohistochemistry showed ER-alpha immunoreactive neurons in the dorsal half of the spinal cord, i.e., dorsal horn, dorsal intermediate gray areas (dorsal...
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