Pain & Central Nervous System Week
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Amyotrophic Lateral Sclerosis
Increased TGF-beta 1 is linked to advanced and/or longterm disease
March 31st, 2003
Increased TGF-beta 1 is linked to advanced and/or longterm disease. According to recent research from Poland, "Previous investigations have shown that TGF-beta 1 may protect neurons against excitotoxic and oxidative damage and may inhibit apoptosis. The aim of this study was to investigate the role of TGF-beta 1 in patients with amyotrophic lateral sclerosis (ALS). The study involved 24 ALS patients and 15 controls. "The ALS patients were divided into groups according to their clinical status, and duration of ALS. TGF-beta 1 molecules in serum and cerebrospinal fluid (CSF) were measured by ELISA. Results showed that TGF-beta 1 concentrations in...
Source: Pain & Central Nervous System Week (2003-03-31)
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