Pain & Central Nervous System Week
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Blood Brain Barrier
Activated T cells directly affect endothelial cells in inflammation
March 31st, 2003
Activated T cells directly affect endothelial cells in inflammation. According to a study from England, "Neuroinflammation is characterized by immune cell infiltration across the blood brain barrier, a process instrumental in neuronal cell death. In neuroinflammation, the blood brain barrier is also damaged, and the consequences of activated lymphocytes on the integrity of the blood brain barrier are not well characterized. Utilizing an in vitro blood brain barrier model, we demonstrate that endothelial cell viability and barrier integrity are directly altered following lymphocyte exposure." Tan and coauthors concluded: "The effect of activated...
Source: Pain & Central Nervous System Week (2003-03-31)
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