Pain & Central Nervous System Week
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CNS Lymphoma
Expression of BCA-1 may influence tumor development and localization to CNS
March 31st, 2003
Expression of BCA-1 may influence tumor development and localization to the central nervous system. According to a study from the United States, "Primary central nervous system lymphoma (PCNSL) is a rare but often rapidly fatal form of non-Hodgkin B-cell lymphoma that arises within the central nervous system (CNS) and has a low propensity to metastasize. "We performed immunohistochemistry on formalin-fixed, paraffin-embedded brain biopsy specimens from 24 patients with PCNSL to investigate the expression of B cell-attracting chemokine 1 (BCA-1, CXCL13), a lymphoid chemokine involved in B-cell compartmental homing within secondary lymphoid organs and...
Source: Pain & Central Nervous System Week (2003-03-31)
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