Pain & Central Nervous System Week
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Endodontics
Mu-opioid receptors are found in human dental pulp
March 31st, 2003
Mu-opioid receptors are found in human dental pulp. "Studies in both animal and clinical models suggest that opioids exert their analgesic effects not only through activation of receptors in the CNS but also through interaction with peripheral opioid receptors. This study evaluated the presence and distribution of mu-opioid receptors in human dental pulp," researchers in the United States report. "Human third molars indicated for extraction were removed, fixed in 4% paraformaldehyde and 0.2% picric acid, and decalcified in 10% EDTA and 7.5% polyvinylpyrrolidone. The teeth were cut using a cryostat, and the avidin-biotin peroxidase...
Source: Pain & Central Nervous System Week (2003-03-31)
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