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Pain & Central Nervous System Week

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Ischemic Stroke



Many factors influence the effects of therapeutic angiogenesis in the brain



March 31st, 2003

Many factors influence the effects of therapeutic angiogenesis in the brain.

"Angiogenesis is an intricately regulated phenomenon. Its mechanisms in the ischemic brain have not been clearly elucidated. The authors investigated expression of angiogenesis-related genes using a complementary DNA (cDNA) array method as well as Western blotting and immunohistochemistry, and compared these studies with a temporal profile of angiogenesis in mouse brains after ischemia," researchers in the United States reported.

"The number of vessels significantly increased 3 days after injury, and proliferating endothelial cells increased as early as 1 day. This means...


Source: Pain & Central Nervous System Week (2003-03-31)

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