Pain & Central Nervous System Week
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Multiple Sclerosis
Intrathecal IgM synthesis is an indicator of very poor prognosis
March 31st, 2003
Intrathecal IgM synthesis is an indicator of very poor prognosis. According to recent research from Spain, "Intrathecal IgM synthesis (ITMS) predicts a worse evolution in the first stages of multiple sclerosis (MS). The aim of this study was the followup of a group of relapsing-remitting MS patients for a longer time to evaluate whether the ITMS implies a poor prognosis. Oligoclonal IgM bands were performed in 29 MS patients followed up from 5-16 years. "Time to conversion to secondary-progressivc MS (SPMS), time elapsed to reach a disability of 6 in the Expanded Disability Status Scale (EDSS), percentage of patients with a benign MS, and changes...
Source: Pain & Central Nervous System Week (2003-03-31)
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