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Pain & Central Nervous System Week

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Stem Cell Research



Several oligodendrocyte progenitor cell subsets identified



March 31st, 2003

Several oligodendrocyte progenitor cell subsets have been identified and characterized.

"Oligodendrocytes, the myelin-producing cells in the central nervous system, represent a large portion of the total number of cells in the human brain," researchers in the United States explained.

"Using cell-specific markers and antibodies to ventral homeodomain transcription factors, NKX2.1 and DLX2," S. Rakic and colleagues at the University of Connecticut found "that a subpopulation of early oligodendrocyte progenitor cells (OPCs) in the human telencephalon may originate in the ganglionic eminence (GE)."

"DLX2-labeled OPCs form a...


Source: Pain & Central Nervous System Week (2003-03-31)

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