Pain & Central Nervous System Week
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Transplant Medicine
Retinal precursor cells express functional neuronal receptors
March 31st, 2003
Retinal precursor cells express functional neuronal receptors. According to a study from the United States, "R28 retinal progenitor cells offer the potential to replace damaged neurons; however, their ability to differentiate into the appropriate phenotype may depend on whether they express glutamatergic and GABAergic receptors. "Whole cell recordings and immunocytochemistry were used to identify glutamatergic and GABAergic receptors on proliferating R28 cells. R28 cells lacked voltage-gated channels; however, they produced inward currents when non-NMDA, NMDA, GABAa and GABAb receptor agonists were perfused onto the cells. R28 cells were...
Source: Pain & Central Nervous System Week (2003-03-31)
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