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Pain and Central Nervous System Week

Susan Hasty, Publisher

Table of Contents . . . June 23rd, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pain and Central Nervous System Week | Other Publications

Stem Cells - Chemical turns stem cells into neurons

Stroke - Patients may retain continuous motion ability

Brain Tumors - Nottingham academics develop new nanotechnology for treatment

Dementia - More research needed to determine usefulness of routine screening

Neuroscience - Protein kinase C gene transfer accelerates motor response alterations in rats

Schizophrenia - Study supports efficacy of first long-acting, newer-generation treatment

Acute Ischemic Stroke - Phase III trials of Cerovive initiated

Acute Lymphoblastic Leukemia - Minimal residual disease monitoring in cerebrospinal fluid can predict relapse

Adverse Drug Effects - Reactions to NSAIDs are reversible except for in chronic urticaria

Alzheimer Disease - Choroid plexus in the aging brain produces less CSF, clears amyloid slowly

Alzheimer Disease - New patent awarded for proteoglycan transgenic mice

Alzheimer Disease - Pro-brain derived neurotrophic factor is decreased in parietal cortex

Alzheimer Disease - Two painkillers fail to slow disease progress

Autoimmune Encephalomyelitis - Vitamin D-3 analog therapy combined with bisphosphonate may prevent bone loss

Borna Disease Virus - Persistent CNS infection in animals and humans have behavioral peculiarities

Brachial Plexus Palsy - Determining surgical indications is one of the most important considerations

Brain Cancer - Glioblastoma and meningioma have differential vascular networks

Brain Infections - Cerebral histoplasmosis patients may not have fever, systemic toxicity symptoms

Brain Inflammation - Dextromethorphan inhibits microglial activation, protecting neurons

Brain Tumors - Acid-sensing ion channels are present in malignant gliomas

Brain Tumors - Glioma cells are capable of converting CPT-11 to SN-38

Brain Tumors - Perturbation of hyaluronan interactions inhibits malignant properties of glioma

Cancer Therapy - Texaphrins show promise for brain tumor patients

Castleman Disease - Report of Castleman disease presenting with a solitary meningeal mass in a child

Cell Biology - 'Kiss-and-run' rules the inner lives of neurons

Cerebral Thromboembolism - Microsnare removes intraprocedural middle cerebral artery clot fragment

Chagas Disease - Nitric oxide produced to fight Trypanosoma cruzi is neuronal and cardiotoxic

Collaborations - Alliance aims to discover, develop new drugs for stroke treatment

Epilepsy - Patients more vulnerable to behavioral side effects

Facial Nerve Injury - Knowledge of nerve anatomy, physiology, and microsurgery are key to management

Female Sexual Dysfunction - Positive phase II efficacy data released on intranasal apomorphine for FSD

Finance - Third NIH grant awarded for cerebral blood flow technology development

Heart Histology - Distribution of neuropeptide receptors Y1 and Y2 in tissues may be uneven

Hypertension - Lack of estrogen keeps blood pressure high in middle-aged female rats

Ischemia - Phase II trials begin for ischemic stroke

Malpractice Insurance - Patients lose access to neurological care, according to survey

Meningitis Vaccine - Catch-up vaccination campaign for Haemophilus influenzae effective

Multiple Sclerosis - Data on patients treated with Avonex for up to 8 years presented

Multiple Sclerosis - Data: Rebif more effective than Avonex in reducing frequency of relapses

Negative Regulation Mechanism - Dopamine uptake is slowed by dopamine transporter binding to alpha-synuclein

Neonatal Asphyxia - NF-kappa B is activated in blood macrophages; increases predict level of risk

Nervous System - Integrins play an active role in all stages of neural development and activity

Neurobiology - Researchers describe cloning embryos from cancer cells

Neurodegenerative Disease - Dementia with neurofilament inclusions is a newly discovered disease

Neuroscience - MR-guidance allows catheter navigation of the intracranial subarachnoid space

Opportunistic Infection -  Bordetella bronchiseptica from household pets can cause meningitis

Osteoarthritis - New collaboration will identify biomarkers for osteoarthritis

Pediatric Neurology - Hippocampal proliferation after birth asphyxia mimics adult responses

Peripheral Neuropathy - Common food sensitivity linked to painful condition

Prion Diseases - Researchers discover possible diagnosis, treatment, vaccine

Prostate Cancer - Phase II trial for BBR 3576 in HRPC presented at ASCO

Schizophrenia - Expression of Fyn as well as its mRNA are increased in the prefrontal cortex

Schizophrenia - Study to hunt for genetic causes

Stem Cell Research - Novel neural cell model enables study of JC virus susceptibility

Toxoplasmosis - Astrocyte and microglial responses are altered, preventing neuronal damage

Toxoplasmosis - Serotyping the infecting strain is now possible with a synthetic peptide ELISA

Trends - New report shows continuing opportunities in eight biopharma sectors

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