Pain and Central Nervous System Week
Susan Hasty, Publisher
Table of Contents . . . July 21st, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pain and Central Nervous System Week | Other Publications
Multiple Sclerosis - Relapsing-remitting men have more CD3 positive cells producing TNF-alpha
Neuronal Lesions - Activated microglia may be responsible for neuronal degeneration
Alzheimer Disease - Enrollment begins in phase II MPC-7869 trial for Alzheimer disease
Alzheimer Disease - Statin drugs may help reduce, prevent Alzheimer disease
Cell Biology - Researchers pinpoint role that cell surface proteins play in brain function
Multiple Sclerosis - Normal-appearing white matter increase is suggested as part of pathogenesis
AMD - Agreement established to develop and market Lucentis
Alzheimer Disease - Phase III trial with Phenserine initiated in Europe
Arthritis - First commercial size batch of Flexogan completed
Axonal Growth Control - GFR alpha 1 has GDNF-dependent and independent nerve growth properties
Bipolar Disorder - Lamictal wins FDA approval
Brain Tumors - Glioblastoma multiform can arise at prior head injury site
Cerebral Ischemic Events - Stroke may occur from endothelium toxicity and coagulation abnormalities
Cerebral Malaria - CCR2 does not play key role in pathogenesis
Cerebrospinal Fluid Leak - CE Mark granted for European commercialization of DuraSeal
Chronic Pain - 2,500th spinal cord stimulation system implanted
Creutzfeldt-Jakob Disease - Brain innoculation with attenuated prions protects indefinitely from virulence
Diabetes Complications - Scientists don't known which genes are associated with diabetic retinopathy
Dry Eye - NDA submitted for diquafosol tetrasodium
E. Coli Complex I - Some mutants with less deamino-NADH oxidase were sensitive to decylubiquinone
Gangliosidosis - GM2 gangliosidosis mimics a brain stem tumor in a 3-year-old girl
Geriatrics - Computer-aided cognitive training might delay mental deficits in the elderly
Guillain-Barre Syndrome - Some patients have anti-GM1 IgG antibodies; these can induce immunoactivation
Infectious Disease Epidemiology - Nested PCR testing aids typing of meningitis-causing enteroviruses
Malignant Glioma - SEK20 million given for brain tumor research
Meningitis Therapy - Ertapenem active against resistant pneumococci
Metabolic Disease - Adeno-associated virus type 1 corrects storage lesions in enzyme-deficient mice
Metastatic Ocular Melanoma - Company presents clinical results using Ceplene
Migraine - Zomig nasal spray proven to be fastest patient-friendly triptan
Multiple Sclerosis - Largest real-life study shows advantages with 2 years of Avonex
Multiple Sclerosis - Quantitative magnetic-resonance-based techniques can monitor MS evolution
Muscular Dystrophy - Chimeraplast-mediated exon skipping restores muscle cell dystrophin expression
Neurodegenerative Disease - Scientists on track for early diagnosis
Neurological Disorder - Anti-neuronal nuclear autoantibody type 2 is rare, but associated with cancers
Neurology - Human hand skin ennervation is reactive to PGP 9.5; a subset reacts to GAP-43
Neuroscience - Endogenous amyloid precursor protein modulates apoptosis in neurons
Neuroscience - Individual factors supercede familial elements in those with cluster headaches
Neuroscience - Statins usher in angiogenesis and nervous system regeneration after a stroke
Neuroscience - Treatment of spinal cord arteriovenous shunts can be managed with embolization
Oligodendrocyte Apoptosis - Interleukin-1 beta needs other cell products to achieve glutamate excitotoxicity
Ophthalmology - Some viruses are promising vectors for intraocular gene delivery
Opioid Addiction - Chronic opioid use lowers cdk5, p35; increases neurofilament phosphorylation
Pain Medicine - Epidural fentanyl volume does not affect labor analgesia or ambulation ability
Pain Medicine - Surgery relieves pain associated with osteoporotic spinal fracture
Parkinson Disease - Gene implicated in nonfamilial form of disease
Parkinson Disease - Increased risk in the Irish might be due to mutation affecting mitochondria
Q Fever - Coxiella burnetii completely sequenced, possible pathogenic proteins found
Retinopathy of Prematurity - Protecting vessel loss in the eyes of premature infants
Seizure Control - Extended Phenytoin sodium capsules receive approval
Spinal Meningiomas - Tamoxifen therapy may play a role in the genesis of multiple spinal meningiomas
Spinal Surgery - Psoas abscess is a risk following anterior spinal fusion or implants
Stem Cell Research - Researchers find stem cells with potential to repair muscle, produce blood cells
Stem Cell Research - SOX genes involved in retinoic acid-induced neural differentiation
Stem Cell Transplantation - Mesial temporal sclerosis may be result of cyclosporin A toxicity
Strabismus Surgery - Double vision can be caused by myasthenia gravis
Stroke - N-Acetyl cysteine may protect against brain injury in focal cerebral ischemia
Temporal Lobe Epilepsy - Phosphorylation of eIF2 alpha by NO may inhibit protein translation
Traumatic Brain Injury - Many survivors don't return to routine lives
Visual Deterioration - Reversible CNS demyelination is possible in autoimmune polyglandular syndrome
West Nile Fever - Acute paralysis can be symptom of infection
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