HIV/AIDS Gene Therapy
Novel vectors may aid treatment of HIV-related brain damage
Published in Pain and Central Nervous System Week, August 4th, 2003
"Gene therapy to treat primary and secondary CNS diseases, including neuro-AIDS, has not yet been effective," researchers in the United States noted. "New approaches to delivering therapeutic genes to the central nervous system are therefore required."
"Recombinant SV40 vectors (rSV40) transduce both dividing and quiescent cells efficiently," and so were tested by P. Cordelier and coauthors at Jefferson Medical College in Philadelphia "for their ability to deliver anti-HIV-1 transgenes to terminally...
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