Pain and Central Nervous System Week

Mergers and Acquisitions - Neurology companies merge to develop neurological disorder therapies

Mergers and Acquisitions - Pain management practice to be acquired

Mergers and Acquisitions - Physiome Sciences announces merger

Multiple Sclerosis - DNA therapeutics reported to be powerful approach to autoimmune disease

Multiple Sclerosis - Metallothionein expression in MS patients is higher in inactive lesions

Multiple Sclerosis - Mutant CCR5 gene may improve outcome for MS patients

Narcolepsy - Hypocretin/orexin system involved in narcolepsy

Nausea - Researcher working on medical patch to deliver marijuana-like drug

Nerve Stimulation - Company receives rights to VNS obesity patent

Neurocysticercosis - Glial fibrillary acidic protein found in CSF of neurocysticercosis patients

Neuroinflammatory Research - Different leukocyte types use different migratory mechanisms in the CNS

Neurological Disorders - Alpha-synuclein gene haplotype not linked to essential tremor

Neurological Disorders - Clinical and neurological features of PARK7-linked parkinsonism described

Neurological Disorders - Novel ALS-associated genetic loci identified

Neuromas - Neuroma does not develop after resection with nerve stump transplanted into vein

Neuroscience -  Cis-acting effects play key role in cerebral gene expression

Neuroscience - Class II HDAC mRNA upregulated during rat hippocampal progenitor differentiation

Neuroscience - Glucocorticoids affect NMDA receptor expression during adolescence

Neuroscience - Organotypic brain slices lacking blood flow contain capillaries and neurons

Neuroscience - Perinatal exposure to lead or cadmium can be unmasked with enzyme markers

Obstetrics - Maternal stress influences infants' cognitive development and temperament

Obstetrics - Pregnancies complicated by rare meningoceles should trigger cesarean births

Occupational Safety - Far less alcohol needed at lunchtime to impair driving

Olfactory Bulb Function - AMPA receptors react at different rates with different neuron subtypes

Ophthalmology - Restored sight case reveals extent to which vision depends on learning

Pain Medication - New compound acts on peripheral receptors

Pain Medicine - Cannabis trial planned for surgery patients

Pain Medicine - Nociceptin/orphanin FQ and its receptor are potential pain therapy targets

Pain Medicine - Time standards for cesarean anesthesia shouldn't compromise patient health

Parkinson Disease - Adult mouse bone marrow stem cells can become cells of the nervous system

Parkinson Disease - Cytoplasmic inclusions in some neurodegenerative disorders may induce death

Parkinson Disease - Dopamine metabolism gene mutations do not affect Tc-99-TRODAT-1 testing for Parkinson disease

Parkinson Disease - Gene therapy study begins

Parkinson Disease - Ubiquitination pathways may be central to Parkinson's disease

Postoperative Pain - Patient-controlled regional anesthesia offers advantages for home use

Prion Disease - What causes prion infectivity?

Prions - Prion protein trafficking studies providing insight into neurodegeneration

Proteomics - Accumulated prion proteins appear to be neurotoxic

Proteomics - Actin filament-stabilizing protein regulates size of dendritic fields

Proteomics - Neuropilin-1 modulates cardiovascular and nervous system development

Psychiatric Drugs - Understanding hospital operations can increase marketing effectiveness

Psychology - Mild prenatal stress associates with enhanced conditioned fear in adult rats

Pulmonary Complications - Lymphomatoid granulomatosis is a risk following renal transplant

RNA Transcription - Scientists find gene that controls severity of neurological disease in mice

Snake Venom Research - Crotoxin is the active Crotalus inhibitor of macrophage phagocytosis

Spine Surgery - FDA approves image-guided navigation system for U.S. market

Stem Cell Research - Neuropeptide Y enhances proliferation of hippocampal neuron precursors

Stroke - Extended, progressive physical therapy aids stroke survivors' mobility

Stroke - FDA clearance granted for thermal regulation system

Stroke - NIH grant will fund study of communication deficits

Subarachnoid Hemorrhage - Positive results reported from phase II trial for clazosentan

Substance Abuse - Neurons involved in drug addiction relapse identified

Systemic Lupus Erythematosus - Infection with parvovirus B-19 is extremely similar; perhaps B-19 initiates SLE

Topical Pain Relief - Flexogan shipped to Canadian wholesaler

Vision-associated Cancer - Paraneoplastic visual disorder, autoimmune optic neuritis, has cancer risk

West Nile Virus - Agreement signed to continue development of methylene blue