Published in Pain and Central Nervous System Week, September 29th, 2003
"Recent developments in stem-cell and gene therapy will require methods to monitor stem-cell survival and integration repeatedly and non-invasively with a high temporal and spatial resolution in vivo. The aim of this study was to visualize embryonic and neuronal stem cells with standard contrast agents using a conventional clinical 1.5-Tesla scanner," scientists in Germany reported.
"We therefore modified standard transfection protocols including lipofection (Lipofectin and Lipofectamine) and calcium phosphate transfection for the efficient uptake of paramagnetic particles...
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