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Pain and Central Nervous System Week

Susan Hasty, Publisher

Table of Contents . . . February 2nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pain and Central Nervous System Week | Other Publications

Leukodystrophy - Scientists restore crucial myelin in brains of mice

Alzheimer Disease - Company reports positive phase III studies of Namenda

Alzheimer Disease - New drug improves outcomes when added to existing therapy for AD

Alzheimer Disease - New method of distinguishing AD from Lewy body dementia described

Alzheimer Disease - Understanding normal aging may provide the key to AD prevention

Alzheimer Disease - Using vitamin E and C supplements together may reduce AD risk

Anesthesia - 510(k) filed with FDA for next generation monitor

Angiology - Estrogen protects cells from certain death after an ischemic stroke

Anxiety - Is listening to your heart bad for your emotional health?

Autism - Population-based study of autism genetics launches

Back Pain - EpiCept provides update on two deals made in 2003

Stroke - Discovery changes ideas about damage from strokes

Bipolar Disorder - Bipolar I disorder biobank collection launched

Brain Remodeling - Juggling students have skill on the brain

Brain Tumors - A 10-degree reverse Trendelenburg position can reduce pressure during craniotomy

Brain Tumors - Gliadel prolongs survival and time to relapse in some glioma patients

Brain Tumors - Idarubicin unlikely to be used for treating primary CNS tumors

Cardiovascular Disease - Homocysteinylated transthyretin may contribute to pathogenesis

Cell Biology - Research examines role of copper, iron in diseases

Cerebral Malaria - Common P. falciparum parasites can cause cerebral malaria in children

Chronic Pain - Primary endpoint achieved in Prialt phase III trial

Cognition - Antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion

Neurodegeneration - Proteasome inhibition arrests neurite outgrowth

Cognition - Somatotropic-axis deficiency affects brain substrates of selective attention

Collaborations - Development, marketing agreement signed for milnacipran

Collaborations - Neurion expands collaboration on HERG ion channel and drug development

Creativity - Study proves wisdom of advice to "sleep on it"

Creutzfeldt Jakob Disease - Action needed to prevent spread of vCJD via blood

Developmental Biology - Regulating folate receptors during folate deficiency

Drug Development - Company donates patent to Columbia University

Drug Development - Tentative approvals granted for Modafinil, Topiramate

Endocrinology - Vasopressin receptor V1b is crucial in times of both stress and rest

Evolutionary Biology - Gene may be key to evolution of larger human brain

Neurology - Fibroblast growth factor-2 gene delivery regenerates adult axon growth

Evolutionary Biology - Primates trade smell for sight

Finance - Neurology company announces $19M private placement

Geriatrics - Amyloidosis modifier genes found in less amyloidogenic A/J mouse strain

Glioblastoma - Iressa phase II trial data published

Glioblastoma - Scientific journal reports on ZFP repression of VEGF-A

Gynecology - An integrated approach is required for diagnosing vaginismus correctly

HIV/AIDS Neuroscience - Opioids can impair neuroprotective effects of retinoids

Headaches - Survey: Most migraine sufferers misdiagnose severe head pain

Heart Failure - Reduced brainstem NOS contributes to enhanced sympathetic drive

Hormone Therapy - Drop in hormone therapy use shows doctors heed research findings

Parkinson Disease - Brain-derived neurotrophic factor controls dopamine D3 receptor expression

Huntington Disease - Simple sugar could prevent degenerative disorder

Infectious Disease - Vertebral cryptococcosis can mimic tuberculosis

Information Technology - Electronic patient diaries distributed for phase III trial of back pain therapy

Insomnnia - A pill-free route to better sleep for elderly

Intraoperative Awareness - Published study results show BIS monitoring reduces intraoperative awareness

Long-Term Care - Nursing homes may need help instituting clinical practice guidelines

Memory - Rat brain reverberations during sleep described

Mergers and Acquisitions - Northwest Toxicology to be acquired by LabOne

Mergers and Acquisitions - Pain relief company completes merger

Motor Control - Brain offers an ultra-fast neural code at your fingertips

Stem-Cell Research - Hematopoietic progenitor subset expresses neural genes

Multiple Sclerosis - High intake of vitamin D linked to reduced risk of MS

Multiple Sclerosis - Taking vitamin D supplements lowers women's risk of MS

Neural Repair - Keck Foundation grant launches interdisciplinary brain research at Illinois

Neurodegeneration - Metabotropic glutamate receptor agonist prevents neuropathological changes

Neuroscience - G protein modules voltage-gated calcium channels

Neuroscience - Kinase inhibitors on TGF-beta induced upregulation of Kv1.3 K+ channels

Neuroscience - VEGF plays a significant role in maintaining nervous system integrity

Nicotine Addiction - Hidden cues that make smokers light up

Niemann-Pick Disease - Niemann-Pick type C disease associated with peripheral neuropathy

Pain Medicine - Drugs in obstetrical epidurals are not linked to chronic adhesive arachnoiditis

Alcoholism - Adolescent rodents experience milder hangover effects than do adult rodents

Pain Medicine - Sex differences account for pain response and treatment outcomes

Pain Medicine - Temporomandibular pain in women aligns with menstrual cycle phases

Paraplegia - Understanding nerve degeneration in spastic paraplegia

Personnel - Ivy Bernhardson named Hazelden general counsel

Personnel - Management additions announced at neurotechnology company

Postoperative Pain - Results of the postoperative pain management project are described

Protein Kinase C - p190RhoGAP plays role in protein kinase C epsilon morphological changes

Receptor Studies - Negative feedback involved in release of substance P from afferent fibers

Reproductive Medicine - Chronic morphine exposure during puberty won't alter rodent maternal behavior

Sandhoff Disease - Autoantibodies at large in Sandhoff disease

Alcoholism - Dependence gene identified

St. John's Wort - Hyperforin enhances proteolytic processing of beta-amyloid precursor protein

Stem-Cell Research - Bax and Bak regulate size of neural stem-cell pool

Stress Response - Melanocortin receptor ligands affect neuronal activities in rat model

Stroke - Risk for lowered cognitive performance is greater in people at high risk for stroke

Stroke - Study documents benefits of acupuncture

Substance Abuse - Ecstasy affects memory, new international study shows

Substance Abuse - Heavy drinkers use narcotics to relieve back pain, despite possible interactions

Trauma - Keeping synapses clean may hold key to fear-conditioning

Weight Loss - Dieters seek alternatives to ephedra

Weight Loss - Study suggests dieters shouldn't give up - slimming hormone waits to be unleashed

Alcoholism - Genetic variation may influence drinking to relieve social anxiety, improve mood

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