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Pain and Central Nervous System Week

Susan Hasty, Publisher

Table of Contents . . . March 1st, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pain and Central Nervous System Week | Other Publications

Brain Injury - Immortalizing cells could aid brain and spinal cord repair

Cerebral Palsy - Newborn brain injuries stem from infections, not delivery

Genetic Disorder - Neuromyopathy occurs in mitochondrial trifunctional protein deficiency

Ischemic Stroke - Second messenger activation underlies brain hyperpermeability during hypoxia

Parkinson Disease - Clozapine effective for controlling dyskinesias

Stroke Epidemiology - Study in children challenges primary theory for "stroke belt"

Alcoholism - Quick fixes for dangerous youth drinking can work

Alzheimer Disease - Genes influence memory in families with AD

Alzheimer Disease - Pathological amyloid formation orchestrated by secretory pathway

Alzheimer Disease - Scientists identify compound that may offer new Alzheimer treatment

Amyotrophic Lateral Sclerosis - Final efficacy results awaited as ALS trial of Ikomio moves forward

Ankylosing Spondylitis - Phase III trial initiated to explore use of Humira

Atherosclerosis - Interactions between ibuprofen and lipoproteins in blood plasma discovered

Autism - Special training may help people recognize faces

Brain Hematoma - MRI and CT can be used to diagnose intracerebral hematoma

Brain Tumor Model - Genetic patterns were stable in human malignant glioma xenografted in nude mice

Breast Cancer - FDA accepts NDA with priority review for RSR13

Breast Pain - New estrogen inhibitor in phase II development

Business Update - Pharmaceutical company announces dismissal of all lawsuits

CNS Diseases - FLAIR-MRI can detect abnormal hyperintensity within the subarachnoid space

Cardiovascular Disease - PET can elucidate regional sympathetic function during heart disease

Cell Division - Research shows how cells ensure genetic material shared evenly between daughters

Cerebral Malaria - Synthetic prototype of P. falciparum GPI developed

Chronic Fatigue Syndrome - Phase III CFS clinical trial complete

Cognition - Mild cognitive impairment may be trigger for pharmacological treatment

Collaborations - Labopharm to develop once-daily formulation of trazodone

Complementary and Alternative Medicine - Research describes why valerian calms us down

Diabetic Neuropathy - Alpha-oxoaldehyde metabolism involved in diabetic complications

Diet and Nutrition - Prenatal mercury exposure via mother's diet can impair certain brain functions

Drug Abuse - Report shows 56% of opiate dependencies begin through legal prescriptions

Drug Development - Antimicrobial diflunisal hydrazide-hydrazones synthesized

Dyslexia - Brain scans being used to study learning disorder

Dyslexia - Dyslexics not doomed to life of reading difficulties

Dyslexia - Scientists look into brains of children with dyslexia

Dysmenorrhea - Positive results reported from phase II study of lidocaine vaginal gel

Endocrinology - Fetal sex hormone exposure may predispose humans to schizophrenia

Epilepsy - Pharmaceutical company announces acquisition of epilepsy product candidate

Finance - Company raises $19.5M to advance ion channel drug discovery and development

Genetic Disorder - Notch3 mutation pattern suggests gain-of-function mechanism for CADASIL

Genomics - Biotechnology and medical genomics partnership awards research grants

HIV/AIDS Dementia - CXCR4 mediates gp120 neurotoxicity in cerebellar granule cells

Healthcare Access - Magellan Health Services announces developments with TennCare contracts

Hormone Replacement Therapy - FDA updates hormone replacement warnings

Hormone Replacement Therapy - HRT no boon to cognitive function in older women

Imaging - Early, noninvasive method to assess Down risk a success

Immunizations - Iowa Senator wants ban on vaccines containing thimerosal

Infectious Disease - Panfungal PCR useful for cerebral aspergillosis diagnosis

Insomnia - Study shows how stress may affect sleep patterns

Leukemia Therapy - Late CMV PRP reported after stem-cell transplantation

Lung Carcinoma - Gamma knife stereotactic radiosurgery is useful for solitary brain metastases

Malaria Therapy - High-dose artemisinin has D2 receptor-mediated sedative effect

Mental Healthcare - Iowa woman pushes for help in care for mental disabilities

Mergers and Acquisitions - Neurologic Rehabilitation and Research Unit of UCLA acquired

Metabolic Syndrome - Chronic kidney disease likely in people with syndrome x

Migraine - Imitrex available in a new formulation

Motor Control - Researchers pinpoint brain areas that process reality, illusion

Multiple Sclerosis - Multiple sclerosis susceptibility mapped to HLA-DR locus in African Americans

Multiple Sclerosis - Preliminary data presented on ATL1102 phase I study

Muscular Dystrophy - FDA Orphan Drug Status filed for muscular dystrophy treatment

Nerve Conduction - Conduction studies detect ulnar nerve entrapment in carpal tunnel syndrome

Neuroblastoma - Combined therapy can benefit neuroblastoma patients in the high-risk group

Neuroscience - An enhanced inhibitory reflex would improve incontinence of neurogenic origin

Neuroscience - Novel helper-dependent canine adenovirus vectors aid neuron transduction

Neuroscience - Superparamagnetic vascular contrast agent depicts brain blood volume on MRIs

Neuroscience - Uncoupling protein 2 is novel player in neuroprotection

Obstetrics - Geomagnetic disturbances at birth may be linked to a risk for schizophrenia

Osteoarthritis - FDA approves Orthovisc; Anika to receive $20M milestone payment

Pain - Intranasal Fentanyl for breakthrough pain shows rapid delivery in study

Pain Medicine - Menstrual symptoms and pain overlap in women with irritable bowel syndrome

Parkinson Disease - $6 Million awarded for research

Parkinson Disease - Parkinson groups award more than $4M through Community Fast Track program

Perception - Paying more attention to object changes its perceived appearance

Personnel - Drug delivery company appoints new VP, finance and administration

Personnel - Drug discovery company announces new vice president

Postoperative Plegia - Some anesthetic agents negatively affect motor evoked potentials

Prion Disease - Advances in species barrier in human and animal prion diseases reviewed

Regulatory Issues - Florida moves against one of state's top Medicaid drug prescribers

Sleep Disorder - Hypocretin-1 increases in cerebrospinal fluid after REM sleep deprivation

Stroke - "Bat saliva" drug and new MRI techniques offer hope for acute stroke treatment

Stroke - Cholesterol drugs may lower risk for mental impairment after stroke

Stroke - Cool brain opens stroke treatment window

Stroke - Lifetime risk higher for women, those with high blood pressure

Stroke - Trial for acute stroke shows magnesium sulphate may benefit some patients

Stroke Risk - Lucky number? Seven factors may increase clot-buster use for stroke

Substance Abuse - New study guides parents in helping teens avoid marijuana use

Substance Abuse - Prescription drug abuse a growing problem in America

Tuberculosis Therapy - Rifampicin reduces focal ischemia-induced brain damage

West Nile Virus - WNV infection in kidney transplant recipient reported

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