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Pain and Central Nervous System Week

Susan Hasty, Publisher

Table of Contents . . . May 10th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pain and Central Nervous System Week | Other Publications

Alzheimer Disease - Can curry protect against neurodegenerative diseases?

Cerebral Palsy - Technological tools augment botulinum toxin therapy for pediatric spasticity

Generic Drugs - Generic versions of pain medication, oral contraceptives launched

Geriatrics - Psychosis syndromes prevail in some patients with Alzheimer disease

Prion Disease - Quinacrine is candidate for the treatment of prion diseases

Addiction Medicine - Clinic establishes research program to predict and prevent addictions

Addiction Medicine - Neonatal methamphetamine exposure has long-term effects on cognitive function

Alzheimer Disease - Alzheimer drug candidate reduces most common form of dementia in elderly

Alzheimer Disease - American Academy of Neurology awards 2004 Potamkin Prize to two scientists

Alzheimer Disease - Article highlights challenges for alternative Alzheimer researchers

Alzheimer Disease - BACE 1 cleaves amyloid-beta precursor protein

Alzheimer Disease - Glucose metabolism changes lead to tau hyperphosphorylation

Alzheimer Disease - Positive results announced in on-going phase II extension study for Alzhemed

Alzheimer Disease - Study: Statins boost cognition in the elderly

Amyotrophic Lateral Sclerosis - Gene mutation found for a form of juvenile-onset motor neuron disease

Animal Model - Model for study of multiple wounds in the diabetic mouse validated

Batten Disease - Motifs target Batten disease protein to lysosomes in neuronal cells

Bladder Dysfunction - Pergolide ameliorates nocturia in female Parkinson disease patients

Bovine Spongiform Encephalopathy - Kansas leaders asks USDA for flexibility on downer cattle

Bovine Spongiform Encephalopathy - Mad cow testing issue divides cattle industry

Brain Cancer - Cathepsin B inhibition suppresses angiogenesis in human glioblastoma cells

Business & Finance - Exclusive distribution agreement for spinal implants amended

Central Nervous System Cancer - New variations of CNS neoplasms are emerging

Circadian Rhythm - Animals exposed to 24-hour light retain wake-sleep habits

Circadian Rhythm - Researchers explore "early bird" and "night owl" sleep patterns in rats

Clinical Trials - Company announces completion of clinical trials for Lorazepam

Cognition - Cognitive function independent prognostic factor in survival of glioma patients

Cognitive Function - Moderate iron deficiency affects cognitive performance of young women

Depression - Unpublished studies suggest most SSRIs unsuitable for children

Diabetic Neuropathy - Magnetic resonance imaging of the diabetic foot reviewed

Drug Delivery - SpeedLyser thrombolytic catheter launched

Drug Resistance - Companies team to offer ABC transporter assays

Emotion - Noticing the mistakes of others may shed light on learning process

Endocrinology - Sex steroids influence the effects DHEA has on cognition in menopausal women

Environmental Health - Brief exposure to chlorpyrifos during neurulation affects brain development

Epilepsy - Pivotal clinical trial for Intercept Epilepsy Control System begins

Epstein-Barr Virus - Researchers look at viral triggers for multiple sclerosis in children

Estrogen Therapy - Hormone maker comments on WHI estrogen-only study data

Ethics - Is it right to boost brainpower with implants?

Fetal Alcohol Disorders - Experts agree to focus on range of disorders stemming from maternal drinking

Fetal Alcohol Syndrome - High-tech "phrenology" aims to identify children who need health services

Fetal Medicine - Exposure to cocaine generates oxidative stress in the fetal rat brain

Finance - Lab company announces strong first quarter results

Finance - Pharmaceutical company announces filing of registration statement

Fitness - Exercise helps out older people

Fitness - Single bout of exercise helpful or harmful to sleep?

Genomics - Collaboration with p53 and p63, p73 responds to cell genotoxic damage

Glaucoma Vaccine - Vaccination for glaucoma being developed

Glioblastoma - Lack of brain specific angiogenesis inhibitor-1 in brain tumors forecasts death

Gynecological Urology - Patients and physicians must collaborate to treat interstitial cystitis

Hearing Research - Cochlear ablation in mice lacking SHP-1 results in neural cell death

Huntington Disease - Cytoplasmic aggregates block axonal transport in Huntington model

Immunology - GABAB receptors modulate microglial interleukin release

Insulin - Possible mechanisms of insulin antinociception described

Ischemia - Ethanol protects against ischemic brain injury

Malaria - Transcriptional changes during severe malaria identified

Mergers & Acquisitions - Workers' compensation company acquired by managed-care firm

Migraine - Topiramate reduces frequency of headaches

Movement Disorders - Research seeks to unravel the secrets of the brain's smallest cells

Multiple Sclerosis - MS patients with fatigue may have abnormal sleep cycles

Multiple Sclerosis - Mixed results reported from Fampridine-SR trials

Neurodegeneration - Marriage helps men to accept multiple sclerosis-related impairment

Neurodegeneration - Role for neuronal insulin resistance in neurodegenerative diseases

Neurology - Genetic studies may reveal the cause of primary and secondary microcephaly

Neuroscience - Alcohol and other drugs stem brain development by causing neuronal suicide

Neuroscience - Bombesin/gastrin-releasing receptors in the BLA regulate memory consolidation

Neuroscience - Presenilin-1 and calcium stores regulate neuronal glutamate uptake

Neuroscience - Virus-mediated gene transfer reverses rubrospinal neuron atrophy

Neurosyphilis - HIV infection delays post-treatment normalization

Neurotoxicity - Nitric oxide induces apoptosis in early-stage nerve injury from limb tourniquet

Nicotine Addiction - Prenatal nicotine primes adolescent brain for addiction

Obstetrics - Epidural analgesia for labor pain improves maternal respiratory function

Obstetrics - Spinal, epidural anesthetics are equally effective in cesarean section delivery

Osteoarthritis - Menthol in topical creams provides pain relief

Parkinson Disease - FDA approves Apokyn for the acute treatment of episodes of immobility

Parkinson Disease - Nitric oxide links bulk of sporadic and familial Parkinson disease

Parkinson Disease - Single chain antibody fragments inhibit aggregation of alpha-synuclein

Parkinson Disease Risk Factor - Central obesity increases risk of Parkinson disease

Perception - Brain scans show humans stimulated in the same way by the same things

Personnel - Biotechnology company announces new senior VP, chief financial officer

Personnel - Former Merck executive appointed president at Selfhelpworks, Inc.

Personnel - Fred B. Parks, PhD, joins board of directors of medical-technology company

Personnel - Medical products manufacturer names VP of global marketing and strategy

Prion Disease - Hyperbaric oxygen enhances expression of prion and heat shock proteins

Prion Disease - Variations in infectious protein determine prion strain differences

Proteomics - Crystal structure of anti-morphine antibody 9B1 determined

Psychology - Gender influences teacher ratings of attention deficit hyperactivity disorder

Sedatives - Low-dose of ketamine effective and safe in children, concludes research

Slipped Disc - Treating a common lower back condition without surgery

Spinal Epidural Abscess - Delay in diagnosing spinal epidural abscess can result in residual deficits

Spinal Muscular Atrophy - Group awards $1.125 million in grants to support SMA research efforts

Stem Cell Transplantation - Blood cell donation linked to lower pain and fatigue compared to marrow donation

Tobacco Use - In utero nicotine exposure has a negative effect on fetal brain tissues

Toxicology - Prenatal exposure to methylphenidate hydrochloride alters the behavior of rats

Wound Care - EGF-induced mitosis increases SLPI levels in keratinocytes

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