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Pain and Central Nervous System Week

Susan Hasty, Publisher

Table of Contents . . . May 17th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pain and Central Nervous System Week | Other Publications

Antiseizure Medication - Gabapentin controls seizures in children receiving chemotherapy

Brain Tumor - Epigenetic downregulation of CTMP transcription common in glioblastomas

Gynecology - Effective treatments for interstitial cystitis are just over the horizon

Gynecology - Pain location defines how chronic pain mediates psychological response

Medical Devices - Portable neuromuscular stimulator shows promise for paraplegics

Pain Medicine - Gene based therapy will provide new options for treating chronic pain

AIDS Therapy - FDA-approved study launched to treat AIDS patients in virologic failure

Addiction Medicine - Ecstasy alters the neurochemistry of the neonatal rat

Adverse Drug Effects - Agents used for treating epileptic children may affect bone health

Alzheimer Disease - 1-40 and 1-42 Beta amyloid antibodies now available

Alzheimer Disease - Glutamate receptor upregulates amyloid precursor protein secretion

Alzheimer Disease - New study results show benefit for AD patients taking Lipitor

Alzheimer Disease - Rab6 membrane association dependent on cellular phosphorylation events

Alzheimer Disease - Recent discoveries pave the way toward new treatments

Alzheimer Disease - Researchers uncover genes involved in early stages of AD

Alzheimer Disease - Spheron developments for Alzheimer disease announced

Amyotrophic Lateral Sclerosis - Veterans have increased risk of neuromuscular disease

Analgesics - Opioid peptide with mu agonist/delta antagonist properties reported

Anesthesia - Bispectral Index Monitor fails to predict adequate sedation in intubated adults

Angiology - Neuropeptide Y is sympathetic modulator in saphenous vein biopsies

Ankylosing Spondylitis - FDA accepts BLA for Remicade

Anticancer Therapy - Neurotoxicity of anticancer agents tested in microglial cell cultures

Aphasia - Improved mood tied to better language ability

Arteriosclerosis - Spinal cord stimulation effective for treatment of peripheral vascular disease

Attention Deficit Hyperactivity Disorder - Study updates genetics of ADHD

Brain Development - Human frontal cortex development depends on G protein-coupled receptor

Brain Development - Maternal marijuana consumption alters L1 expression in the male fetal brain

Brain Injury - Hurricane Floyd boosted abuse and nonabuse brain injuries in children

Cancer Diagnosis - Scientists use protein "fingerprints" to identify nervous system diseases

Cancer Therapy - Tumor choline/water signal reduction reflects efficacy of temozolomide therapy

Central Nervous System - Human CD34+ cells differentiate into microglia

Charcot-Marie-Tooth Disease - Novel mutation found in MPZ gene in Charcot-Marie-Tooth patient

Cognition - Rhesus monkeys exposed to cocaine in utero have neurobehavioral deficits

DNA Sequence - Human chromosome 13 DNA sequenced and analyzed

Depression - Severity of depressed mood affects stroke risk

Dermatology - Delayed thrombospondin 2 production restrains optimal healing in aged mice

Diabetic Neuropathy - Apoptosis of vasopressinergic hypothalamic neurons occurs in diabetes

Diagnostic Imaging - 18FDG PET scans contain artifacts and pitfalls

Diagnostics - 3-D MR digital subtraction angiography aids visualization of tumor dynamics

Diagnostics - Infant skull radiographs can reveal a variety of pathologic conditions

Diagnostics - Solitary tumefactive demyelinating lesions are atypical by imaging

Diagnostics - Ultrasound detects postoperative complications after vaginal tape placement

Drug Screening - Commercial drug discovery services launched

Drug Target - Transient receptor potential ion channels potential drug targets

Dyslexia - Study bolsters evidence that dyslexia is more common in boys

Dystonia - Botulinum toxin can help musicians with motor control problems

Environmental Health - Maternal dioxin harms neural tube development in nonhuman primates

Environmental Toxins - Increased brain tumor mortality at petroleum exploration and extraction facility

Epilepsy - Condition presents unique problems for women

Epilepsy - In utero exposure to antiepileptic drugs can cause birth defects

Epilepsy - Monthly hormonal changes can exacerbate seizures in women with epilepsy

Epilepsy - New guidelines will improve treatment and access for patients

Epilepsy - Professional groups publish treatment guidelines evaluating antiepileptic drugs

Epilepsy - Sodium channel gene mutation identified in case of familial epilepsy

Epilepsy - Study reveals cause of loss of consciousness during seizures

Epilepsy - Surgery for treatment of temporal-lobe epilepsy varies among ethnic groups

Epilepsy - Surgery successful treatment option for certain seizures

Finance - CNS-focused pharma announces exercise of underwriters' over-allotment option

Finance - Drug company closes on $10.26M; funds to support development of ALS therapy

Finance - Drug-delivery company completes stock offering

Finance - Lexapro maker reports earnings per share of $0.38 for fiscal fourth quarter

Finance - Pharmaceutical firm reports loss of $0.12 per share, clinical update

HIV/AIDS Dementia - Cognitive problems common in sub-Saharan HIV-positive patients

Hypertension - Arterial baroreflex signals depend on neuronal NOS

Hypertension Therapy - Anti-hypertensive alpha-lactorphin does not affect rat behavior

Hypotension - New treatment for intractable low blood pressure controls dizziness, fainting

Imaging - PET scanning promising in diagnosing cancer-related neurological disorders

Influenza Vaccine - Guillain-Barre coexists with pericarditis after influenza vaccination

Laryngology - Apraxia of speech in children is focus of new OHSU grant

Lyme Disease - Antibodies preferentially produced during neuroborreliosis identified

Mammography - Women use different strategies to cope with the pain of mammograms

Medical Devices - Heart resynchronization resolves pacemaker-induced mitral regurgitation

Meniere Disease - Surgery remains a safe, viable option for treatment of Meniere disease

Mental Health - Brain-derived neurotrophic factor relates to mood disorders in women and men

Mental Health - Cannabinoid CB1 receptor inverse agonist has antidepressant effects

Migraine - Study shows coenzyme Q10 may prevent headaches

Molecular Biology - Measurement clarifies role between protein structure and cell adhesion

Motor Neuron Diseases - New neurons can get out of spinal cord

Multiple Sclerosis - Alzheimer disease drug improves memory, cognition in MS patients

Multiple Sclerosis - Beta interferon dose improves MRI outcomes

Nausea - New data released on potential drug for chemotherapy-induced nausea

Neurodegeneration - Mechanisms of insulin and neurodegenerative disease reviewed

Neurodegenerative Diseases - Early signs that adult bone-marrow stem cells could regenerate brain tissue

Neuromuscular Diseases - Creatine is safe, but not effective, in pediatric neuromuscular diseases

Neuroscience - Anti-MuSK antibodies in seronegative myasthenia gravis characterized

Neuroscience - Ca2+ and CaM kinase regulate neurofilament expression

Neuroscience - Effects of BDNF and NT3 different on calcium-binding protein expression

Neuroscience - Expression of glucagon-like peptide-1 shown in nodose ganglion cells

Neuroscience - Functions of lipoprotein receptors in neurons reviewed

Neuroscience - Kainic acid upregulates uncoupling protein-2 mRNA expression in brain

Neuroscience - Nogo and axon regeneration reviewed

Neuroscience - Selective imaging reveals how pericytes influence cerebral blood flow

Obstetrics - Antenatal factors associated with maternal infection hamper infant neurology

Pain Control - Benefits of ON-Q PainBuster presented at plastic surgery meeting

Pain Medicine - Researchers on front lines in battle against postoperative pain

Pain Medicine - Study explores controlling pain with your brain

Pain Medicine - Substance P plays role in hyperalgesia after peripheral tissue injury

Pain Medicine - Transderman NTG with etodolac ameliorates chronic post-thoracotomy pain

Paralysis - Pilot study of BrainGate Neural Interface system initiated

Parkinson Disease - APOE gene linked to brain disorder

Parkinson Disease - Brain cell loss starts years before diagnosis

Parkinson Disease - Molecule pumped directly into brain improves Parkinson symptoms

Patents - Forest Laboratories receives notification of ANDA filing for a generic Lexapro

Patents - U.S. patent issued covering treatment of motor neuron disorders

Personnel - Biotechnology company names new vice president, corporate development

Personnel - eRXSYS Inc. adds new member to advisory board

Posttraumatic Stress Disorder - New report finds U.S. unprepared for mental health impact of terrorist acts

Psychology - Endotoxin exposures may cause behavioral disorders such as schizophrenia

Restless Legs Syndrome - Drug effective in treating restless leg syndrome

Schizophrenia - Hormone may offer hope for treating behavior disorders

Schizophrenia - Imaging test could be used to diagnose schizophrenia

Sleep Disorders - Cognitive function assessment available for sleep disorders

Speech - Language "center" of brain shifts with age

Spinal Cord Injury - Robotic technology teaches patients to walk again

Stem Cell Research - Human neural stem cell lines are stable when cultured for long periods

Stroke - Blood pressure drug helps delay brain damage in stroke patients

Stroke - Carotid stent system recommended for approval by FDA panel

Stroke - Mexican Americans at greater risk for stroke than non-Hispanic whites

Stroke Risk - Adolescents binging on marijuana may face higher risk of stroke

Stroke Risk - Migraine with aura, cholesterol increase risk of stroke in women

Toxicology - Lead found in Mexican candies sold in U.S.

Valvular Heart Disease - Possible link seen between Parkinson medication and cardiac valve disease

Vertigo - Treatment rates for vertigo improved by simple movement exercises

Wound Care - The wounds of diabetic patients heal better with hyperbaric oxygen therapy

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